There is insufficient evidence to suggest that rainfall directly affects the frequency of diarrhoea in Chiredzi given that 28% of variation in diarrhoea is due to random variability for rainfall. Other factors could be contributing to spread of diarrhoea. Spatial distribution of diarrhoea could be a function of limited safe water which is a climate issue. Even though rainfall and temperature are inversely related to diarrheal diseases, erratic rainfall can compel people to make use of contaminated water.